The present study aimed to evaluate the acaricidal activity of TANUVAS
nanomethiconenanomedicine, polyherbal spray, and deltamethrin in cross-bred dairy
cattle. This study was conducted at Naraikinaru and Pillipakuttai villages in Namakkal
district. A total of 20 animals were randomly distributed in 4 groups, with 5 animals in each
group. Group 1 was taken as control (C), Group II was treated with TANUVAS
nanomethiconenanomedicine, Group III was treated with polyherbal spray, and Group IV was
treated with deltamethrin. All the selected animals were heavily infested with ticks (6-7
ticks/square inch) at the beginning of the experiment. The number of ticks in the select area (3
inches x 3 inches) was counted during pre-treatment (0 days) and post-treatment (7, 14, 21,
28, and 35 days) periods. The efficacy of all treatments was calculated. There was a complete
disappearance of ticks from the animal sprayed with TANUVAS nanomethicone and
deltamethrin after 3 days of treatment and reinfestation did not occur up to the 28th day and
the 14th day in TANUVAS nanomethicone and deltamethrin respectively. Further, the tick
population was significantly (P<0.01) decreased in polyherbal spray up to the 14th day after
treatment and significantly (P<0.01) increased from the 21st day. The results of this study
revealed that TANUVAS nanomethicone nanomedicine gives a longer period of protection
and effectively controls tick infestation in cross-bred dairy cattle.